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1 December 2002 LINGUAL SQUAMOUS CELL CARCINOMA IN A CALIFORNIA SEA LION (ZALOPHUS CALIFORNIANUS)
Tsuneo Sato, Tomomi Higuchi, Hisashi Shibuya, Shigeo Ohba, Sadao Nogami, Wataru Shirai, Hideaki Watanabe, Shigeaki Honda
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Abstract

A 28-yr-old female California sea lion (Zalophus californianus) in a commercial aquarium developed an ulcerated lingual tumor and died. Necropsy revealed a moderately differentiated squamous cell carcinoma. Immunohistochemical staining and electron microscopic studies revealed that the tumor cells were strongly positive with anti–keratin-cytokeratin antibody and had abundant tonofibrils and desmosomes. The neoplasm had metastasized to a mandibular lymph node.

Tsuneo Sato, Tomomi Higuchi, Hisashi Shibuya, Shigeo Ohba, Sadao Nogami, Wataru Shirai, Hideaki Watanabe, and Shigeaki Honda "LINGUAL SQUAMOUS CELL CARCINOMA IN A CALIFORNIA SEA LION (ZALOPHUS CALIFORNIANUS)," Journal of Zoo and Wildlife Medicine 33(4), 367-370, (1 December 2002). https://doi.org/10.1638/1042-7260(2002)033[0367:LSCCIA]2.0.CO;2
Received: 28 December 2001; Published: 1 December 2002
KEYWORDS
California sea lion
electron microscopy
immunohistochemical staining
lingual
squamous cell carcinoma
Zalophus californianus
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